Ciliates display promise for foreign gene expression

Two Models for Gene Assembly in Ciliates

Two models for gene assembly in ciliates have been proposed and investigated in the last few years. The DNA manipulations postulated in the two models are very different: one model is intramolecular – a single DNA molecule is involved here, folding on itself according to various patterns, while the other is intermolecular – two DNA molecules may be involved here, hybridizing with each other. Co...

Robustness of ciliates gene assembly

Ciliates are highly complex single-cell organisms, yet very successful from evolutionary point of view they emerged eon years ago and derived into many thousands of known species. Robustness may have an essential contribution to their survival. In this paper, we discuss the robustness of ciliates gene assembly, a process that transforms a diploid micronucleus to a macronucleus and involves mass...

Foreign gene expression in yeast: a review.

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The Promise and Limitations of Gene Expression Analysis

Developments in the fields of genomics, transcriptomics, and proteomics have modified the definition of complex diseases in recent years. To have increasingly precise protein, genomic, and gene expression signatures would further define disease, advance treatment, and enhance the field of personalized medicine. In the area of cardiovascular disease, these specific areas have not followed parall...

Gene expression profiling in MS: a fulfilled promise?